According to Mien-Chie Hung, Ph.D., professor and chair of University of Texas MD Anderson’s Department of Molecular and Cellular Oncology in Houston, tumor cells are often exposed to low oxygen levels (hypoxia) which in turn causes the epidermal growth factor receptor (EGFR) to send signals that interfere with miRNA processing thus promoting cancer.
http://bionews-tx.com/news/2013/05/28/md-anderson-researchers-when-oxygen-is-short-egfr-prevents-maturation-of-cancer-fighting-mirnas/
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